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Hence, long known to cause excess lipid accumulation (Peckham et al., 1962), HFDs have also been shown to stimulate the production of reactive oxygen species (ROS), thus leading to oxidative stress (Auberval et al., 2014)

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It is important to recognize that while the disease affects the SN neurons and cause the classical symptoms, other brain regions, such as respiratory nuclei, also undergo degeneration

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All experiments were performed independently for at least twice