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Under a hyperglycemic condition, ROS accumulates, damages DNA and proteins, and injures cardiomyocytes

Clin Exp Med 17 , 131139 (2017)

European Journal of Clinical Nutrition , 72(1), 105-111

To facilitate systematic comparison, the sources, key anti-inflammatory mechanisms, targeted signaling pathways, disease models, and representative preclinical evidence of major PDEVs are summarized (Table 1)

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In both mouse models of endometriosis and human endometriotic stromal cells, inhibition of the Raf/MEK/ERK pathway has been shown to induce apoptosis, effectively suppressing the proliferation and migration of endometriotic cells (63)