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Phosphorylation of axin, a Wnt signal negative regulator, by glycogen synthase kinase-3beta regulates its stability

2 However, studies on the crosstalk between metabolic regulation and immune system is inseparable from the regulation of immune functions

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Deficient E-cadherin expression leads to the loss of epidermal melanocyte adhesion during situations of oxidative or mechanical stress.11 Furthermore, a relevant role of integrins and the Melanoma Inhibitory Activity (MIA) protein has been identified

In addition, increased mtDNA mutations have been reported in germ cells subjected to maternal hyperglycemia and aging [46]

Elucidating this issue is complicated by multiple confounding factors, including population heterogeneity, medication use, dietary and lifestyle variations, disease staging, and inconsistencies in research methodologies