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In another article published in 2021, Saha et al

J.LamattinaL.EstelleM.et al (2011)

Severe Adverse Reactions Severe reactions to cyanocobalamin are rare but serious

Biomed Rep 4:519522

Another study suggested that DNA damage in adipocytes can disturb secretory function and adipocyte metabolism and activate the p53 signaling pathway, inducing adipose tissue inflammation and insulin resistance