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PLoS One 8 , e76057, (2013)

As has been reported with grapefruit juice, time-dependent inhibition of CYP3A can result in irreversible loss of protein, requiring de novo synthesis to restore enzyme activity over a time course dictated by the half-life of CYP3A protein

Their mechanisms arent entirely understood

Respiratory symptoms occur in about 40% of people with dermatomyositis, and in these people, the symptoms may slowly progress, contributing to increased morbidity and mortality

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Enhanced Production of Recombinant Protein by Fusion Expression with Ssp DnaB Mini-Intein in the Baculovirus Expression System