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These findings are encouraging but require confirmation in larger scale studies

An overdose of vitamin B12 through diet is hardly possible and also not known, since the required transport protein IF (intrinsic factor) and absorption via the intestinal mucosa are two major barriers

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For dietary deficiency where absorption is intact, oral B12 supplementation may be appropriate after initial loading doses

Baclofen generally has a lower potential for addiction compared to benzodiazepines