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Significant differences in normalized body mass index have been observed between groups treated and not treated with GH, but no significant differences have been found in parameters related to obstructive sleep apnea (OSA) in these groups ( Isolated and idiopathic growth hormone deficiency (GHD) occurs when there is a deficiency of GH without any specific syndrome or disease (i.e., the deficit is unrelated to a genetic disorder or a particular pathological condition)

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The RBD region on the S1 subunit recognizes anchor point(s) on the host cell surface, whereas the S2 subunit facilitates fusion of viral envelope with the host cell membrane after proteolytic cleavage of S1/S2 site to mediate viral entry 68,69

MelikianNChowienczykPMacCarthyPAWilliamsILWheatcroftSBSherwoodRet al

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