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64,144,145 Several other SNPs in genes such as TNF-related apoptosis-inducing ligand (TRAIL), 68 Interleukin-6, 42,43 Signal Transducer and Activator of Transcription 3 (STAT3), 62 Adiponectin, 25 Leptin receptor, 45 peroxisome proliferator-activated receptor-alpha (PPAR), 58 PPAR, 59 peroxisome proliferator-activated receptor gamma-coactivator 1 alpha (PGC-1) 57 have also been correlated with the NAFLD disease progression (Table 1)

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[DOI] [PMC free article] [PubMed] [Google Scholar] 16.Shan X., Hu P., Ni L., Shen L., Zhang Y., Ji Z., Cui Y., Guo M., Wang H., Ran L., Yang K., Wang T., Wang L., Chen B., Yao Z., Wu Y., Yu Q., Serine metabolism orchestrates macrophage polarization by regulating the IGF1-p38 axis

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2003 meta-analysis: A meta-analysis of 21 clinical trials including a total of 1,204 adults with mild cognitive impairment or mild Alzheimer's disease examined the effects of 1.5 to 3.0 g/day acetyl-L-carnitine versus placebo for 3 to 12 months