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Immunoprecipitation experiments have revealed that 30 parasite proteins affinity purify with RhopH2 (Pantaleo et al., 2010), the resulting reduction in AE1 affinity for the cytoskeleton and consequential membrane destabilization occur at the end of the cell cycle ( Another erythrocyte voltage-dependent anion channel (VDAC), which is either expressed alone or as a component of the peripheral-type benzodiazepine receptor (PBR) complex, is the VDAC

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Thus, it is postulated that the factors that cause migraines have a similar capacity to increase oxidative stress, which in turn facilitates the onset of migraines