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the NF-kB pathway) independent of ligand engagement (121123)

It remains unclear whether GAD is involved in SLMVs transport to the plasma membrane, in analogy to GABAergic neurons (see also Section 3.3)

The breakdown process of BCAAs is similar in all species, initially forming branched-chain -keto acids (BCKAs) via branched-chain amino acid transferase (BCATs) and transferring nitrogen to nitrogen receptors (the most common nitrogen receptor is -ketoglutaric acid (-KG) to form glutamate)

While cystine is generally considered the rate-limiting amino acid for GSH synthesis [47], glutamate also plays a crucial role in GSH production, especially in cancer cells with a high demand for GSH

Induced cultivations were kept on separate incubator from uninduced ones to avoid any effect of the highly volatile cyclohexanone

Further research has demonstrated that this dysregulation of the negative feedback mechanism plays a vital role in PTSD, potentially being a key factor causing the persistence of chronic stress states (Sriram et al., 2012)