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Overall, Val significantly impacts meat quality and metabolism in animals, however, its effects on the meat quality and metabolism of Tibetan sheep remain unclear

For example, signaling through the chemokine receptor, CCR2, or Fc receptor promote inflammation through upregulation of the IL-6 pathway, leading to activation of signal transducer and activator of transcription 3 (STAT3) by ischemic endothelium (Arbaizar-Rovirosa et al., 2023)