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The mechanistic target of rapamycin (mTOR) is a central nutrient sensor that integrates growth signals with anabolism to fulfil biosynthetic and bioenergetic requirements

Figure 9 Fer-1 and NAC can alleviate cisplatin-induced AKI in Gstm1/Gstt1 -DKO mice We conducted a rescue experiment to validate that the primary mode of tubular cell death is ferroptosis in DKO mice exposed to cisplatin