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40 criteria for the five patients that underwent muscle biopsy found that three patients were rated as having a definite MD and two patients were rated as having probable MD

2.3 Primary detection methods of TMAO The detection of TMAO can be achieved through various methods, including enzyme-linked immunosorbent assay (ELISA), Liquid chromatography-mass spectrometry (LC-MS/MS), Nuclear magnetic resonance spectroscopy (NMR), gas chromatography, and electrochemical sensors

Carnitine palmitoyltransferase 1C The brain-specific carnitine palmitoyltransferase 1C (CPT1C) displays high-affinity to bind malonyl-CoA, but its enzymatic activity cannot be observed using conventional assays 43

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Malaguarnera M, Pistone G, Astuto M, Dell'Arte S, Finocchiaro G, Lo Giudice E, Pennisi G: L-Carnitine in the treatment of mild or moderate hepatic encephalopathy

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