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[Abstract]2026 Feb 18:2026.02.17.706363

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More rarely, GO can be found in patients with hypothyroid autoimmune thyroiditis or in subjects with subclinical evidence of thyroid autoimmunity, but with no thyroid dysfunction, and the pathogenesis of these conditions is still a matter of debate ( Oxidative Stress in Graves Orbitopathy Oxidative stress is defined as the disruption of the balance between the production and the elimination of reactive oxygen species (ROS), which causes a remarkable damage of several cell components, namely proteins, lipids, membranes, and nucleic acids ( Figure 1 )

Available from: Molina J-M, Squires K, Sax PE, Cahn P, Lombaard J, DeJesus E, et al

[Google Scholar] Chen Y, Lu Y, Lee RJ, Xiang G (2020)

The association of APOE 4 with cognitive function over the adult life course and incidence of dementia: 20 years follow-up of the Whitehall II study