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A phosphoenzyme mimic, overlapping catalytic sites and reaction coordinate motion for human NAMPT

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Methionine in turn is required for the synthesis of S-adenosylmethionine, a methyl group donor used in many biological methylation reactions, including the methylation of a number of sites within DNA, RNA, and proteins ( Figure 1 ) (3)

When administering orally it should be given with meals, for absorption