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doi: 10.1016/j.bbabio.2011.07.003

[DOI] [PubMed] [Google Scholar] 122.Furgaa A., Fijakowski ., Nowaczyk A., Saat R., Saat K

Ferroptosis is an iron-dependent form of cell death driven by phospholipid peroxidation, characterized by the loss of GPX4 activity, collapse of antioxidant defenses, and accumulation of lipid peroxides ( Mechanistically, autophagy modulates ferroptosis sensitivity through ferritinophagy, the selective degradation of ferritin that increases labile iron and enhances lipid peroxidation

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In cardiovascular diseases, markers like succinate, GABA, and TMAO highlight mitochondrial and lipid metabolism dysfunctions

CT26 cells were purchased from the Chinese Academy of Sciences/Stem Cell Bank (Shanghai, China)