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In a rat model of chemically induced colon cancer, inhibition of cell proliferation by aged garlic extract was associated with a reduction in the incidence of precancerous lesions and dysplastic adenomas, but not of adenocarcinomas (72)

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Despite the fundamental role of ER redox regulation in physiology and disease, the identity of ER glutathione transporters remains poorly defined

On the other hand, many researchers place the adaptive immune system at the center of RA disease pathogenesis

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These findings support acalabrutinib-based regimens as effective, chemotherapy-free alternatives in treatment-naive CLL, with AV offering a favorable safety/efficacy balance and AVO achieving the highest PFS but with more toxicity