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Description

Everything known about its effects comes from animal pharmacology [3] [4] [5] , not from controlled human therapeutic trials

Nat Rev Clin Oncol

Following this, the receptors were then embedded in a rectangular 126 x 126 1-palmitoyl-2-oleyl-sn-glycerol-3-phosphocholine (POPC) bilayer (previously built by using the VMD Membrane Builder plugin 1.1 at considering the coordinates retrieved from the OPM database to gain the correct orientation within the membrane, while removing the lipid molecules overlapping the receptor TMD bundle

A systematic review (PMID: 40756949) examined its emerging use in orthopaedic sports medicine, while a 2025 pilot study (PMID: 40131143) provided early human safety data