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doi: 10.3389/fonc.2025.1568391 Received 06 February 2025 Accepted 23 May 2025 Published 09 June 2025 Corrected 17 July 2025 Volume 15 - 2025 Edited by Jianqiang Xu, Dalian University of Technology, China Reviewed by Sivapar V

Advancements in single-cell RNA sequencing have characterized previously unrecognized spatial heterogeneity and immune functions of stromal cells in the lymph nodes (114, 122, 123, 125, 130, 131), suggesting that the disintegration of the highly organized stromal cell structure will impair the anti-cancer immune responses (132)

A reduction in size, number and function of mitochondria is associated with aging, and supporting mitochondria with essential nutrients like B12 and NAD can potentially slow and even reverse the aging process

in vitro 66 LiH.ZhangM.WangD.DongG.ChenZ.LiS.et al (2021b)

Xeloda 500mg Tablet active substance contains capecitabine which is converted to 5-fluoro-2-deoxyuridine monophosphate and 5-fluorouridine triphosphate that incorporates into DNA and RNA strand thus inhibits the protein synthesis process that results in multiplication and spread of cancer