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The most frequent adverse events were dry mouth (46%), hypertension (43%), diarrhea (38%), fatigue (38%), increased aspartate aminotransferase (AST) level (35%), nausea (35%), and constipation (35%)

These findings highlight the importance of GLUD1 in shaping the immune microenvironment and pave the way for the development of tailored immunotherapeutic approaches

doi: 10.1016/j.bbamcr.2019.118535 36 TurcuALVersiniAKheneNGailletCCanequeTMullerSet al

Sourcing is where the real risk sits This is where the regulatory gap actually bites

1 Yet, greater clinical trials would be needed to give scientific evidence for the management of liver disorders

PI3k/AKT signaling pathway: erythropoiesis and beyond