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Furthermore, Syn aggregates reduce GCase activity, forming a self-perpetuating cycle of lysosomal dysfunction and Syn accumulation

In prostate cancer (VCaP) cells, UA regulates critical metabolites and signaling pathways, such as S-adenosylmethionine (SAM), glycolysis, and phospholipid metabolism, while RNA sequencing indicates UAs impact on pathways related to cancer metastasis and oxidative stress [1081]

Jall, S

Hydrophilic groups such as hydroxyl, carboxyl, and amino groups confer high solubility and dispersibility, while additional functional groups permit chemical modification, enabling the formation of functionalized supramolecular structures (109) ( Figure 2 )

It is able to penetrate skin easily regardless of skin type or thickness

J Biol Chem 270:2499525000 Skrzypczak-Jankun E, Zhou K, Mccabe NP, Selman SH, Jankun J (2003) Structure of curcumin in complex with lipoxygenase and its significance in cancer