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Notably, the mTORC1 substrates include ribosomal protein S6 kinase 1 (S6K1) and eIF4E binding protein (4E-BP1), which play key roles in translation 22,39,40,41

In contrast, N -acetyl-l-cysteine (NAC), a precursor of l-cysteine that results in GSH elevation, and thus often used as an antioxidant, significantly reduced rotenone induced cytotoxicity in the RTgill-W1 cells but had no effect in the ASG-10 cells (Fig

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