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The key issue is not interest in peptides, but rigor in mapping mechanism to clinically validated outcomes and controlled human data

By encapsulating drug molecules in nanoparticles, nanoparticle drug delivery systems exhibit the advantage of improved drug loading, less exposure of the drug molecule to metabolic enzymes and drug efflux pumps, longer blood circulation, and facilitation of drug passage through the cell membrane via transcytosis instead of passive diffusion

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CP functions as an inactive prodrug, necessitating enzymatic and chemical activation

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