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It's estimated that almost 40% of the US population is B12 deficient, ranging from mild deficiencies that can cause weakness, tiredness, mood changes and neurological problems, to significant deficiencies that are associated with anemia, easy bruising, numbness in the fingers and toes, difficult walking, depression, memory loss and dementia

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Most commonly, you reconstitute the lyophilized powder with bacteriostatic water and inject it subcutaneously twice daily at 250-500mcg per dose