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Farahzadi R, Sanaat Z, Movassaghpour-Akbari AA, Fathi E, Montazersaheb S

Competitive experiments revealed that the addition of urea significantly weakened the drug effect, confirming that the targeting molecule was indeed UreI and providing direct evidence for drug-channel lock-and-key delivery

PMID: 12553851.

This flexibility represents an important practical advantage, allowing patients to choose a schedule that best fits their lifestyle and daily routine

Therefore, targeting the metabolic vulnerabilities of these cells might selectively eradicate them and improve the overall survival of patients with AML