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thus, injured or damaged articular cartilage remains one of the most difficult tissues to treat

It improved the quality of life of patients and the effects of radiotherapy

Standard tirzepatide dosing starts at 2.5 mg weekly for the first four weeks, then increases to 5 mg

DNA fragmentation due to apoptosis was assessed by terminal deoxynucleotidyl transferase-mediated dUTP nick-end-labeling (TUNEL) assay using a DeadEnd Fluorometric TUNEL system kit (Promega, USA) per the kit instructions

231 , 232 In addition, drugs that selectively kill senescent cells (senolytics) or drugs that prevent the senescence growth arrest (e.g., statins) are being explored