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This raises an intriguing possibility that other transcriptional regulators are involved that facilitate cellular adaptation when oxygen tension is limiting for HIF- 1

- You frequently experience low energy levels or other symptoms of deficiency

Funding The study has been approved by Shantou Science and Technology Support, China (No:200812225264260)

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10.1016/j.bbabio.2012.12.010 Biochim

Mice bearing orthotopic xenografts of NTRK2 -KO DIPG in the brainstem or NTRK2 -KO paediatric cortical glioblastoma in the frontal cortex exhibited a marked increase in overall survival compared with littermate controls xenografted with NTRK2 wild-type cells (Fig