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doi: 10.1073/pnas.0914036107

Thus, mTORC2 acts as a negative regulator of autophagy through the AKT/FOXO3 signaling axis in skeletal muscle

[Abstract]2026 May 6;74(17):13876-13886

Moreover, ROS inhibit hepatocyte secretion of VLDL and promote hepatic insulin resistance, inducing liver fat accumulation and necro-inflammation

In our study, physiological and biochemical responses were significantly enhanced under arsenic stress, and brassinosteroids (BRs) played a crucial role in further strengthening these responses by modulating antioxidant defense, nutrient balance, and stress tolerance mechanisms 41

We confirmed that GCLC-KO mice have significantly reduced GCLC and glutathione levels, and an elevated ratio of oxidized to total glutathione in their brains (Fig