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Effects on skin of Stichopus japonicus viscera extracts detected with saponin including holothurin A: Down-regulation of melanin synthesis and Up-regulation of neocollagenesis mediated by ERK signaling pathway

The latter peculiar feature may be adopted for drug delivery applications since the release can be modulated and programmed by a specific pH stimulus

Comprising a short chain of nine amino acids, DSIP is recognized for its role in modulating sleep-wake cycles, neuroendocrine function, and stress responses

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Insulin sensitization of human preadipocytes through glucocorticoid hormone induction of forkhead transcription factors

Kanaji et al