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Degeneration of the optic nerve results in cupping, which is the distinctive appearance of the optic disc and accompanying loss of vision (97)

BRD4 and CRBN intracellular target engagement assays An Echo acoustic liquid handler (Labcyte) was used to transfer compound in 10-point dose response (100 nL transfers) to empty wells on a white, tissue culture treated 384 well plate

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[email protected] This article was submitted to Frontiers in Genetics of Aging, a specialty of Frontiers in Genetics

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