Apart from the traditional targeted drugs that aim at inhibiting glutamine transporters and GLS, an increasing number of promising targets directly or indirectly involved in glutamine metabolic pathway have been studied, with the aims of achieving an antitumor effect by blocking the glutamine-dependent metabolism in tumor cells (61,93)
The enol form, vinyl alcohol (CH 2 =CHOH) exists in equilibrium with acetaldehyde to the extent of approximately one molecule per 30 000 (Hagemeyer, 1978)
Daily cocaine self-administration under long-access conditions augments restraint-induced increases in plasma corticosterone and impairs glucocorticoid receptor-mediated negative feedback in rats
The experimental process was to pre-treat MDA-MB-231 cells for 20 min with a low concentration (10 M) of NRC-03 or NRC-07 20 minutes and then added a gradient concentration of cisplatin
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Parkinson's disease: Convergence on synaptic homeostasis