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This review focuses on the functional importance of the various PTMs in p53-mediated ferroptosis, specifically in the context of carcinogenesis and cancer prevention (Figure 4)

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Gradual changes often go unnoticed without baseline comparison

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The duration of response was nearly twice as long in the treatment arm, at 18.4 months, compared to the control arm, with an objective response rate (ORR) of 58%

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Cell 65 , 932940 (2017)

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