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Perhaps more importantly, the data provided by Schultz et al

10.1016/j.freeradbiomed.2018.01.019 27 JiaJ.LiQ.SunQ.YangN.ChenK.XixiY.et al (2020)

Heterozygous TBK1 mutations impair TLR3 immunity and underlie herpes simplex encephalitis of childhood

& Melone, M

however, the underlying mechanisms are unclear

These nanoparticles can be designed to release drugs in reaction to particular chemical alterations in hypoxic conditions, such as elevated acidity or the presence of enzymes