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Near the critical pressure, the effect of fluid density is predominant, thus, a moderate increase in temperature leads to a large decrease in the fluid density, and therefore, to a decrease in solute solubility

Citrulline rapidly declines in LPS(+ IFN-)-primed BMDMs, and ASS1-mediated citrulline depletion is responsible for JAK2STAT-1 signaling activation and proinflammatory cytokine generation, stimulating the M1 phenotype [280]

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Overall, this comprehensive experimental design allowed for the evaluation of Epitalons effects on key aspects of oocyte physiology, including oxidative stress response, mitochondrial function, spindle morphology, and developmental potential