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10.1093/ajcn/nqac040 [PMC free article: PMC9170474] [PubMed: 35470384] [CrossRef] Zamora-Ros R, Cayssials V, Clries R, Torrents M, Byrnes G, Weiderpass E, et al

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The glucagon pathway in particular produces effects, including thermogenesis and hepatic lipid mobilization, that no prior GLP-1 or GLP-1/GIP compound prepared the body for

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Collectively, the apoE4 variant appears to be associated with low cholesterol and poor lipidation, which, together with domain interactions, decreases its stability leading to impaired neuronal lipid metabolism and changes in lipidome profile that alters the brain innate immunity response to AD pathologies

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In this section, the regulators best characterized to date are described, and additional regulators are presented in Table 1

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