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Based on these trials, TB-500 has been applied in a wide range of doses, starting with as low as 0.5mcg/kg of bodyweight and reaching up to roughly 16,000mcg/kg of bodyweight (1260mg/day) for 10-14 days

Henson JD, Lau LM, Koch S, Martin La Rotta N, Dagg RA, Reddel RR (2017) The C-Circle Assay for alternative-lengthening-of-telomeres activity

Cells were cultured with RPMI 1640 supplemented with 10% FBS, 100 U/mL penicillin and 100 g/mL streptomycin, and then incubated in a humidified atmosphere containing 5% CO 2 at 37C

Finally, PPIs inhibit lysosomal acidification by suppressing the neutrophil vacuolar-type H + ATPase (V-ATPase), which ultimately reduces neutrophil antibacterial activity (Song et al., 2017)

Morotz, G

Example 14: Preparation of exenatide tablets comprising sodium caprate Preparation of the tablets: A homogenous powder blend with 60 mg of exenatide, 3.000 g of sodium caprate, 1.320 g of sorbitol, 780 mg of Avicel PH-101 and 60 mg of magnesium stearate was prepared