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TET enzyme driven epigenetic reprogramming in early embryos and its implication on long-term health

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However, given the inconsistency and heterogeneity of findings, it can be inferred that the effects may vary between different UGT isoforms ( Nicotine, a well-known component of cigarette smoke, also alter metabolic pathways particularly by interfering with Organic Cation Transporters (OCTs) in vitro (Urakami et al., 1998