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ACAD9 (acyl-CoA dehydrogenase-9), a flavin-dependent acyl carrier, is involved in the proper assembly of complex I through binding with assembly factors NDUFAF-1 and Ecsit [42]

10.3109/09513591003686395 60 Van BlerkomJ.DavisP

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The aim of this study is to exploit GSH-responsive AP site capture reagent (AP probe-net), which responses to the elevated glutathione (GSH) levels in the tumor micro-environment (TME), releasing reactive alkoxyamine to trap AP sites and block the APE1-mediated BER for targeted anti-tumor activity against ATC