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miR-141/200c repress SIRT1 and thereby blunt PGC-1 deacetylation/activation, attenuating mitochondrial biogenesis and antioxidant support programs (8184)

J Neural Transm (Vienna) 126 (7):815-840

When your blood sugar spikes, it damages your delicate nerves, and you develop diabetic neuropathy or nerve pain

Research published in Redox Biology found that when cells were exposed to stress, older cells' glutathione levels plummeted to just 10% of their original levels, while younger cells maintained at least 35% of their glutathione