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A double-blind, placebo-controlled trial of lamotrigine for pathological skin picking: treatment efficacy and neurocognitive predictors of response

These results highlight dual-targeted disruption of serine availability as a promising therapeutic strategy to overcome chemotherapy resistance in Np63-driven LUSC

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in the future, potential research studies should determine the CYP2D6 variations in order to use the accurate predicted phenotype in clinical therapy

In short, we used a flexible factorial design depending on time point (after all treatment) and group (NC, SP, ROT, SP + ROT, MH, and MH + ROT), as previously described (1, 2)