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doi: 10.1111/ppa.12893 49 Mndez-LpezE.DonaireL.GoslvezB.Daz-VivancosP.Snchez-PinaM

This enzyme converts anthracyclines to substances that cause severe oxidative stress, irreversible damage to mitochondrial DNA, and disruption of mitochondrial energy metabolism

PMCID: PMC8391 Modi BP, Khan HN, van der Lee R, Wasim M, Haaxma CA, Richmond PA, Drgemller B, Shah S, Salomons G, van der Kloet FM, Vaz FM, van der Crabben SN, Ross CJ, Wasserman WW, van Karnebeek CDM, Awan FR