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Gene expression profile analysis of Drosophila melanogaster selected for resistance to environmental stressors

In addition, APIJNS exhibits efficient CAT-like activity, which can catalyze the production of O 2 from overexpressed H 2 O 2 in TME, which not only alleviates the hypoxia within the tumor lesion, but also converts it into 1 O 2 to activate the photosensitizer ICG and enhance the effect of PDT for synergistic antitumor effects

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Moreover, some other animal studies have reported a similar effect of riboflavin on SOD ( Reference Liang, Liu and Xu 23 , Reference Hirano, Hamajima and Horiuchi 34 , Reference Tumkiratiwong, Tungtrongchitr and Migasena 35 ) , GPx ( Reference Tumkiratiwong, Tungtrongchitr and Migasena 35 , Reference Wang, Mei and Chen 36 ) and catalase ( Reference Tumkiratiwong, Tungtrongchitr and Migasena 35 , Reference Lee, Ye and Jones 37 ) activities