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Description

Induction of phenotypes resembling CuZn-superoxide dismutase deletion in wild-type yeast cells: An in vivo assay for the role of superoxide in the toxicity of redox-cycling compounds

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Documentation of metabolic improvementsincluding changes in hemoglobin A1c, lipid profiles, and blood pressureprovides additional evidence of treatment benefit and may motivate continued adherence to therapy