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[137] found that the sesquiterpene CA-4 in the seed extract of Artemisia argyi exerts anti-inflammatory effects through a dual mechanism: 1) Inhibiting the MAPK pathway (phosphorylation of ERK/JNK), down-regulating the expression of iNOS/COX-2, and blocking the polarization of M1 macrophages

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219,220 Additionally, NF-B serves as a central mediator for the activation initiation signal of the NLRP3 inflammasome, responding to various PRR ligands and cytokines by inducing the transcriptional expression of NLRP3 and pro-IL-1

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Drug withdrawal-induced depression: Serotonergic and plasticity changes in animal models

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Hence, the surface morphology of nanoparticles is a significant factor affecting their properties

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In: Naeem M, Bremont JFJ, Ansari AA, Gill SS (eds) Agrochemicals in soil and environment: impacts and remediation

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