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This finding links 4HNE to ferroptosis, as evidenced by lipid peroxidation, iron accumulation, nuclear translocation of NRF2, decreased GPX4 protein levels, and increased expression of ferroptotic markers, confirming that 4HNE acts as an inducer of ferroptosis [54]

Emodin can suppress cell growth through inducing cell cycle arrest at G0/G1, S and G2/M stages, such as G0/G1 arrest in NSCLC cells via hyaluronan synthase 2 (HAS2)-mediated signaling [461], and S and G2/M phases arrest in liver cancer (Hep G2) cells [456]

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The strong affinity of cyclodextrin-based metalorganic frameworks for acetylene was found to be originated from the CHX (X = O and F) H-bonding interactions within the cyclodextrin-based metalorganic framework confined space (Jin et al