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Remember: only escalate one compound at a time

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Special thanks to the Medical Research and Invention Center Bhumibol Adulyadej Hospital for their funding contribution

Discussion Previously, in a genome-wide siRNA screening of a PD cell model, we identified that the knockdown of three genes ( ALK7 , DYNLRB1 , and GSK3B ), which are associated with the TGFb signaling pathway, was found to mitigate aSyn-induced toxicity [10]