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There is currently no approved human therapeutic use

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Conclusion The choice between vitamin B12 injections and supplements requires careful consideration of individual circumstances, medical history, and treatment goals

Vidal-Alaball J, Butler CC, Potter CC (2006) Comparing costs of intramuscular and oral vitamin B12 administration in primary care: a cost-minimization analysis

A total of 539 patients were enrolled with 359 patients randomized to pemetrexed and 180 patients randomized to placebo