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TB4 is a peptide consisting of 43 amino acids that is found in several tissues, including the spleen, thymus, and peritoneal macrophages

Compounded versions of both are substantially cheaper, typically $200-400 per month depending on pharmacy and dose

Nature 542 , 352356 (2017)

Clin Auton Res 6:111114 Raffaele R, Vecchio I, Giammusso B, Morgia G, Brunetto MB, Rampello L (2002) Efficacy and safety of fixed-dose oral sildenafil in the treatment of sexual dysfunction in depressed patients with idiopathic Parkinsons disease

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Cognitive function, assessed by the MMSE and clock test, and mood, measured by the GDS-15, were evaluated at baseline and study end