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These indicate that TIGAR has PPP-independent antioxidant activity in prolonged cerebral ischemia

Zhou Y, Wang HD, Zhou XM, Fang J, Zhu L, Ding K (2018) N-acetylcysteine amide provides neuroprotection via Nrf2-ARE pathway in a mouse model of traumatic brain injury

requires long-term storage at -20C or 2C to 8C after arrival

doi: 10.3390/nu10030270 127

Targeted Lipoma and Lump Support: Contains L-Carnitine and mushrooms to promote normal fat metabolism and healthy cell growth

While this could indicate that flux through the PPP is necessary to compensate for oxidative processes downstream of glycolysis, it is also possible that optimal PPP flux is needed during the initial steps of activation