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SPE columns (Waters, Milford, MA) were used to separate lipid species, according to a published lipid separation method 78 , and free glycerol content was determined by colorimetric assay (Sigma-Aldrich)

Nozawa, H., Chiu, C

FGF21 also reduces mitochondrial stress in neurons in vitro (273) and in vivo (271), and improves pathology in mouse models of Parkinsons (274) and Alzheimers disease (275)

High Purity (99%): Ensures consistency and reliability in experimental results

One major difference lies in early developmental history

Muscle biopsy is the definitive test to exclude other neuromuscular diseases and assess severity of involvement